António Grilo, PhD

Lonza

I joined Lonza, in the middle of the Swiss Alps, in 2019 as a Process Expert in the Manufacturing Science and Technology (MSAT) group to support bringing to life multiple facilities for biologics production including mammalian, microbial or mRNA technologies – yes we are producing Moderna’s Covid19 Vaccine, but this is only one among many exciting ongoing projects! In the MSAT Team, I have been working as a Data Management SME and I have also been working on process transfer activities, bringing the processes from our development labs and/or from our customers and scaling them up to manufacturing scale.

Before joining Lonza, I obtained a Ph.D. in Chemical Engineering from Imperial College London with a thesis on multi-scale mathematical models for bioprocess development supervised by Professor Athanasios Mantalaris and supported by a Marie Curie grant from the European Commission. During this time, I strengthen my knowledge of upstream bioprocessing (cell culture), process analytics and mathematical modelling using mechanistic modelling and data-driven approaches. As part of my research activities, I had the opportunity to collaborate with scientists from the University of Strathclyde (UK), the University of Aachen (Germany), Bayer (Germany) and the Technical University of Delft (Netherlands). At Imperial College, I was also a Teaching Assistent for Advanced Bioprocess Engineering and Modelling of Biological Systems and co-supervised 2 MSc. students and 2 MEng. students and 1 BSc. student internship. I co-authored 7 scientific publications and presented my work in several international conferences in Europe and the United States.

Prior to my Ph.D., I had worked on downstream processing of biologics at Instituto Superior Tecnico with Professor Ana Azevedo and Professor Raquel Aires-Barros and also at the Purification Process Development Group at Amgen (Seattle, WA, USA). I submitted this work as my MSc. thesis in Biochemical Engineering to Instituto Superior Tecnico being awarded a 20/20. During my degree at Tecnico Lisboa, I studied for 1 year at the Technical University of Denmark with a EU Grant under the Erasmus Programme, after completing my BSc. in Lisbon.